PD-L2/B7-DC/PDCD1LG2 Antibody (TY25) [DyLight 488]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, IHC, IHC-Fr
Clone
TY25
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 488

PD-L2/B7-DC/PDCD1LG2 Antibody (TY25) [DyLight 488] Summary

Immunogen
B7-DC transfected RAW264.7 cells.
Specificity
NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
PDCD1LG2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PD-L2/B7-DC/PDCD1LG2 Antibody (TY25) [DyLight 488]

  • B7-DC
  • bA574F11.2
  • Btdc
  • Butyrophilin B7-DC
  • Butyrophilin-like Protein
  • CD273 antigen
  • CD273
  • CD273PD-1 ligand 2
  • MGC142240
  • PD-1-ligand 2
  • PDCD1L2MGC142238
  • PDCD1LG2
  • PDL2
  • PD-L2
  • PDL2B7DC
  • PD-L2PDCD1 ligand 2
  • programmed cell death 1 ligand 2
  • Programmed death ligand 2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PD-L2/B7-DC/PDCD1LG2 Antibody (NB100-65332G) (0)

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Product General Protocols

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FAQs for PD-L2/B7-DC/PDCD1LG2 Antibody (NB100-65332G) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-65332AF350
Alexa Fluor 405 NB100-65332AF405
Alexa Fluor 488 NB100-65332AF488
Alexa Fluor 532 NB100-65332AF532
Alexa Fluor 594 NB100-65332AF594
Alexa Fluor 647 NB100-65332AF647
Alexa Fluor 700 NB100-65332AF700
Alexa Fluor 750 NB100-65332AF750
Allophycocyanin NB100-65332APC
Biotin NB100-65332B
DyLight 350 NB100-65332UV
DyLight 405 NB100-65332V
DyLight 488 NB100-65332G
DyLight 550 NB100-65332R
DyLight 650 NB100-65332C
DyLight 680 NB100-65332FR
DyLight 755 NB100-65332IR
FITC NB100-65332F
HRP NB100-65332H
Janelia Fluor 549 NB100-65332JF549
Janelia Fluor 646 NB100-65332JF646
PE NB100-65332PE
PerCP NB100-65332PCP

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Bioinformatics

Gene Symbol PDCD1LG2