Reactivity | MuSpecies Glossary |
Applications | Flow, IHC, IHC-Fr |
Clone | TY25 |
Clonality | Monoclonal |
Host | Rat |
Conjugate | DyLight 488 |
Immunogen | B7-DC transfected RAW264.7 cells. |
Specificity | NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor. |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Rat |
Gene | PDCD1LG2 |
Purity | Protein G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein G purified |
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | NB100-65332AF350 | |
Alexa Fluor 405 | NB100-65332AF405 | |
Alexa Fluor 488 | NB100-65332AF488 | |
Alexa Fluor 532 | NB100-65332AF532 | |
Alexa Fluor 594 | NB100-65332AF594 | |
Alexa Fluor 647 | NB100-65332AF647 | |
Alexa Fluor 700 | NB100-65332AF700 | |
Alexa Fluor 750 | NB100-65332AF750 | |
Allophycocyanin | NB100-65332APC | |
Biotin | NB100-65332B | |
DyLight 350 | NB100-65332UV | |
DyLight 405 | NB100-65332V | |
DyLight 488 | NB100-65332G | |
DyLight 550 | NB100-65332R | |
DyLight 650 | NB100-65332C | |
DyLight 680 | NB100-65332FR | |
DyLight 755 | NB100-65332IR | |
FITC | NB100-65332F | |
HRP | NB100-65332H | |
Janelia Fluor 549 | NB100-65332JF549 | |
Janelia Fluor 646 | NB100-65332JF646 | |
PE | NB100-65332PE | |
PerCP | NB100-65332PCP |
Diseases for PD-L2/B7-DC/PDCD1LG2 Antibody (NB100-65332G)Discover more about diseases related to PD-L2/B7-DC/PDCD1LG2 Antibody (NB100-65332G).
| Pathways for PD-L2/B7-DC/PDCD1LG2 Antibody (NB100-65332G)View related products by pathway.
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PTMs for PD-L2/B7-DC/PDCD1LG2 Antibody (NB100-65332G)Learn more about PTMs related to PD-L2/B7-DC/PDCD1LG2 Antibody (NB100-65332G).
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Gene Symbol | PDCD1LG2 |