PD-L2/B7-DC/PDCD1LG2 Products

Description

B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. B7-DC (CD273) has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. B7-DC (CD273) has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Bioinformatics

Uniprot	AAH74766.1 Human NP_079515 Human Q9BQ51 Human
Product By Gene ID	80380
Alternate Names	B7-DC bA574F11.2 Btdc Butyrophilin B7-DC CD273 antigen CD273PD-1 ligand 2 MGC142240 PD-1-ligand 2 PDCD1L2MGC142238 PDL2B7DC PD-L2PDCD1 ligand 2 programmed cell death 1 ligand 2 Programmed death ligand 2