Home » PD-L2/B7-DC/PDCD1LG2 » PD-L2/B7-DC/PDCD1LG2 Antibodies » PD-L2/B7-DC/PDCD1LG2 Antibody (OTI7B10) [Janelia Fluor® 635]

PD-L2/B7-DC/PDCD1LG2 Antibody (OTI7B10) [Janelia Fluor® 635]

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Summary
Product Discontinued
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    • Catalog Number
      NBP2-73306JF635
    • Availability
      Product Discontinued

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PD-L2/B7-DC/PDCD1LG2 Antibody (OTI7B10) [Janelia Fluor® 635] Summary

Immunogen
Full length human recombinant protein of human PDCD1LG2 (NP_079515) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PDCD1LG2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PD-L2/B7-DC/PDCD1LG2 Antibody (OTI7B10) [Janelia Fluor® 635]

  • B7-DC
  • bA574F11.2
  • Btdc
  • Butyrophilin B7-DC
  • Butyrophilin-like Protein
  • CD273 antigen
  • CD273
  • CD273PD-1 ligand 2
  • MGC142240
  • PD-1-ligand 2
  • PDCD1L2MGC142238
  • PDCD1LG2
  • PDL2
  • PD-L2
  • PDL2B7DC
  • PD-L2PDCD1 ligand 2
  • programmed cell death 1 ligand 2
  • Programmed death ligand 2

Background

B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. B7-DC (CD273) has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. B7-DC (CD273) has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PDCD1LG2