PCPTP1 Antibody

Western Blot: PCPTP1 Antibody [H00005801-D01P] - Analysis of PTPRR expression in transfected 293T cell line by PTPRR polyclonal antibody.Lane 1: PTPRR transfected lysate(73.90 KDa).Lane 2: Non-transfected lysate.

Proximity Ligation Assay: PCPTP1 Antibody [H00005801-D01P] - Analysis of protein-protein interactions between PTPRR and MAPK1. HeLa cells were stained with anti-PTPRR rabbit purified polyclonal 1:1200 and anti-MAPK1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Product Discontinued

PCPTP1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: PTPRR (NP_002840.1, 1 a.a. - 657 a.a.) full-length human protein. MRRAVCFPALCLLLNLHAAGCFSGNNDHFLAINQKKSGKPVFIYKHSQDIEKSLDIAPQKIYRHSYHSSSEAQVSKRHQIVNSAFPRPAYDPSLNLLAMDGQDLEVENLPIPAANVIVVTLQMDVNKLNITLLRIFRQGVAAALGLLPQQVHINRLIGKKNSIELFVSPINRKTGISDALPSEEVLRSLNINVLHQSLSQFGITEVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTPRR
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Proximity Ligation Assay
  • Western Blot
• Application Notes: It has been used for WB.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PCPTP1 Antibody

• Ch-1 PTPase
• ch-1PTPase
• DKFZp781C1038
• EC 3.1.3.48
• ECPTP
• EC-PTP
• FLJ34328
• MGC131968
• MGC148170
• NC-PTPCOM1
• PCPTP1
• protein tyrosine phosphatase Cr1PTPase
• protein tyrosine phosphatase, receptor type, R
• protein-tyrosine phosphatase NC-PTPCOM1
• Protein-tyrosine phosphatase PCPTP1
• PTPBR7
• PTPRQ
• PTP-SL
• receptor-type tyrosine-protein phosphatase R
• R-PTP-R

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRR
• Uniprot:
  • NP_002840.1(Human)