PCPTP1 Products

Antibodies
PCPTP1 Antibody
PCPTP1 Antibody
NBP1-84912
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
PCPTP1 Antibody
PCPTP1 Antibody
H00005801-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
PCPTP1 Antibody
PCPTP1 Antibody
H00005801-D01P
Species: Hu
Applications: WB, ELISA, PLA
Host: Rabbit Polyclonal
Lysates
PCPTP1 Overexpression Lysate ...
PCPTP1 Overexpression Lysate (Dena...
H00005801-T01
Species: Hu
Applications: WB
PCPTP1 Overexpression Lysate ...
PCPTP1 Overexpression Lysate (Native)
NBP2-11323
Applications: WB
PCPTP1 Overexpression Lysate ...
PCPTP1 Overexpression Lysate (Native)
NBL1-14987
Applications: WB
Proteins
PCPTP1 Recombinant Protein
PCPTP1 Recombinant Protein
H00005801-P01
Species: Hu
Applications: WB, ELISA, PA
PCPTP1 Recombinant Protein An ...
PCPTP1 Recombinant Protein Antigen
NBP1-84912PEP
Species: Hu
Applications: AC
RNAi
PCPTP1 RNAi
PCPTP1 RNAi
H00005801-R01
Species: Hu
PCPTP1 RNAi
PCPTP1 RNAi
H00005801-R02
Species: Hu

Description

PCPTP1, also known as Receptor-type tyrosine-protein phosphatase R, has 4 isoforms, a 657 amino acid isoform that is 74 kDa, a 412 amino acid isoform t5hat is 47 k Da, a 451 amino acid isoform that is 51 kDa, and a 545 amino acid isoform that is 61 kDa, expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate, sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. The protein is being studied for its involvement in colorectal cancer, episodic ataxia, ataxia, leukemia, prostatitis, and neuronitis. This protein has also been shown to involve MAPK1, MAPK14, MAPK3, MAPK7, and CDH2 in MAPK signaling pathway, EGFR1 Signaling Pathway, Signal transduction Erk Interactions- Inhibition of Erky, and Epithelial Adherens Junctions pathways.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5801
Alternate Names
  • DKFZp781C1038
  • ECPTP
  • EC 3.1.3.48
  • Ch-1PTPase
  • R-PTP-R
  • receptor-type tyrosine-protein phosphatase R
  • PTPRQ
  • protein-tyrosine phosphatase NC-PTPCOM1
  • NC-PTPCOM1
  • protein tyrosine phosphatase Cr1PTPase
  • Protein-tyrosine phosphatase PCPTP1
  • ch-1PTPase
  • PTPBR7
  • Ch-1 PTPase
  • PTP-SL
  • MGC148170
  • PCPTP1
  • MGC131968
  • EC-PTP
  • FLJ34328
  • protein tyrosine phosphatase, receptor type, R

Research Areas for PCPTP1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience

PTMs for PCPTP1

Learn more about PTMs related to PCPTP1.

Phosphorylation
Dephosphorylation
Methylation

Bioinformatics Tool for PCPTP1

Discover related pathways, diseases and genes to PCPTP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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