Pax7 Antibody (SPM613) [FITC]

• Reactivity: Hu, Mu
• Applications: Flow, IHC
• Clone: SPM613
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

Pax7 Antibody (SPM613) [FITC] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)
• Localization: Nuclear
• Marker: Rhabdomyosarcoma Marker
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PAX7
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Use in Flow Cytometry reported in scientific literature (PMID: 32019766).
  Optimal dilution of this antibody should be experimentally determined.
  
  Recommended applications are based on validated applications from the unconjugated base product NBP2-47923. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:32019766).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for Pax7 Antibody (SPM613) [FITC]

• FLJ37460
• HUP1
• paired box 7
• paired box gene 7
• paired box homeotic gene 7
• paired box protein Pax-7
• paired domain gene 7
• PAX7 transcriptional factor
• Pax7
• PAX7B
• RMS2

Background

PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Pax7 Antibody (NBP2-47923F)(1)

Publication using NBP2-47923F

• Reggio A, Rosina M, Krahmer N et al. Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration Life Sci Alliance. [PMID: 32019766] (FLOW, Mouse)

Bioinformatics

• Gene Symbol: PAX7