PAWR / PAR4 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PAWR / PAR4 Antibody Summary

Immunogen
This antibody was made against a protein fragment from the Middle Region
Specificity
This product is specific for Human PAWR.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PAWR
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody is useful in ELISA and Immunohistochemistry-Paraffin.
Publications
Read Publications using 30540002.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs. These products are available in limited quantities. Please enquire about the availability of this product before purchasing.

Alternate Names for PAWR / PAR4 Antibody

  • Par-4
  • PAR4prostate apoptosis response protein 4
  • PRKC apoptosis WT1 regulator protein
  • PRKC, apoptosis, WT1, regulator
  • Prostate apoptosis response 4 protein
  • prostate apoptosis response protein PAR-4
  • transcriptional repressor PAR4
  • WT1-interacting protein

Background

Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PAWR / PAR4 Antibody (30540002)(2)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PAWR
Entrez
Uniprot