PARP4 Antibody

Product Discontinued

PARP4 Antibody Summary

• Immunogen: The antiserum was produced against synthesized peptide derived from human PARP4. The immunogen region is: Internal.
• Specificity: PARP4 Antibody detects endogenous levels of total PARP4 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PARP4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunohistochemistry 1:50 - 1:100
  • Immunohistochemistry-Paraffin 1:50 - 1:100

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PARP4 Antibody

• 193 kDa vault protein
• ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1
• ADPRTL1
• ADPRTL1I-alpha-I-related
• ARTD4
• EC 2.4.2.30
• H5 proline-rich
• KIAA0177
• p193
• PARP4
• PARP-4
• PARPL
• PARP-related
• PARP-related/IalphaI-related H5/proline-rich
• PH5P
• poly (ADP-ribose) polymerase family, member 4
• poly [ADP-ribose] polymerase 4
• poly(ADP-ribose) synthetase
• poly(ADP-ribosyl)transferase-like 1
• Vault poly(ADP-ribose) polymerase
• vault protein, 193-kDa
• VAULT3
• von Willebrand factor A domain containing 5C
• VPARP
• VPARPKIAA0177
• VWA5C

Background

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PARP4
• Uniprot:
  • Q9UKK3(Human)