PAR3/Thrombin Receptor-like 2 Products

Description

Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.

Bioinformatics

Uniprot	O00254 Human
Product By Gene ID	2151
Alternate Names	Coagulation Factor II Receptor-like 2 F2RL2 PAR3 Protease-activated receptor 3 Thrombin Receptor-Like 2

Research Areas for PAR3/Thrombin Receptor-like 2

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GPCR