PALB2 Products

Description

PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.

Bioinformatics

Uniprot	NM_024675 Human NP_078951.2 Human Q86YC2 Human
Product By Gene ID	79728
Alternate Names	DKFZp667I166 DKFZp686E1054 FANCNFLJ21816 partner and localizer of BRCA2 PNCA3

Research Areas for PALB2

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer

Related PALB2 Blog Posts

Check out the latest blog posts on PALB2.

The recent relationship of BRCA1 and 53BP1 The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage.  DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m...    Read more.

Read more PALB2 related blogs.