PADI1 Antibody

Product Discontinued

PADI1 Antibody Summary

• Immunogen: A 15 residue synthetic peptide derived from a domain specific for Human peptidylarginine deiminase type 1 protein.
• Specificity: Peptidylarginine Deiminase Type I. Cross reactivity with other PAD isoforms has not yet been determined
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PADI1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:1000
  • Immunohistochemistry-Paraffin 1:200-1:1000
  • Western Blot 1:200-1:1000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Antiserum
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Lyophilized powder, reconstituted in distilled water.

Alternate Names for PADI1 Antibody

• EC 3.5.3.15
• HPAD10
• hPAD-colony 10
• PAD1
• PDI
• PDI1Protein-arginine deiminase type I
• peptidyl arginine deiminase, type I
• Peptidylarginine deiminase I
• protein-arginine deiminase type-1

Background

Peptidylarginine deiminases (PADs) convert arginine residues in proteins into citrullines. They are suspected to be involved in multiple sclerosis and rheumatoid arthritis pathophysiology, and they play a role in epidermis homeostasis and possibly in regulation of gene expression through histone modification. In humans, five isoforms encoded by the genes PADI1-4, 6 are known so far.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PADI1
• Entrez:
  • 29943(Human)
• Uniprot:
  • Q9ULC6(Human)