PADI1 Products

Description

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq]

Bioinformatics

Product By Gene ID	29943
Alternate Names	EC 3.5.3.15 HPAD10 hPAD-colony 10 PAD1 PDI PDI1Protein-arginine deiminase type I peptidyl arginine deiminase, type I Peptidylarginine deiminase I protein-arginine deiminase type-1

Research Areas for PADI1

Find related products by research area and learn more about each of the different research areas below.

Amino Acids, Drugs and other small molecules
Cancer
Signal Transduction