OVCA1 Antibody [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 405

OVCA1 Antibody [Alexa Fluor® 405] Summary

• Immunogen: DPH1 homolog. (Uniprot# Q9BZG8)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DPH1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for OVCA1 Antibody [Alexa Fluor® 405]

• Diphthamide biosynthesis protein 2 homolog-like 1
• Diphthamide biosynthesis protein 2-like
• diptheria toxin resistance protein required for diphthamide biosynthesis(Saccharomyces)-like 1
• diptheria toxin resistance protein required for diphthamide biosynthesis-like 1
• diptheria toxin resistance protein required for diphthamide biosynthesis-like 1(S. cerevisiae)
• DPH1 homolog (S. cerevisiae)
• DPH1 homolog
• DPH2L
• DPH2L1diphthamide biosynthesis protein 1
• DPH2-like 1
• DPH-like 1 (S. cerevisiae)
• DPH-like 1
• FLJ33211
• hsDph1
• Ovarian cancer-associated gene 1 protein
• ovarian tumor suppressor candidate 1
• OVCA1candidate tumor suppressor in ovarian cancer 1

Background

Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DPH1