ORC3L Antibody

Western Blot: ORC3L Antibody [NBP1-46177] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at 0.04 ug/ml.

Immunohistochemistry: ORC3L Antibody [NBP1-46177] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ORC3 used at a dilution of 1:200 (1ug/ml) Detection: DAB staining using Immunohistochemistry Accessory Kit .

• Reactivity: Hu
• Applications: WB, IHC, IP (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

ORC3L Antibody Summary

• Description: Novus Biologicals Rabbit ORC3L Antibody (NBP1-46177) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen for this product maps to a region between residue 325 and 375 of human Origin Recognition Complex, Subunit 3-like using the numbering given in entry NP_036513.2 (GeneID 23595).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ORC3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ORC3L Antibody

• IMAGE50150
• LAT
• LATHEOorigin recognition complex, subunit 3-like (yeast)
• ORC3Lhomolog of latheo, Drosophila
• origin recognition complex subunit 3
• Origin recognition complex subunit Latheo
• origin recognition complex, subunit 3 (yeast homolog)-like
• origin recognition complex, subunit 3 honolog (yeast)
• origin recognition complex, subunit 3 honolog
• origin recognition complex, subunit 3
• origin recognition complex, subunit 3-like

Background

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ORC3