Oncostatin M/OSM Antibody (17001.31) - Low Endotoxin, Azide and BSA Free

• Reactivity: Hu, Mu(-)
• Applications: WB, ELISA, IHC, B/N
• Clone: 17001.31
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Low Endotoxin, Azide and BSA Free

Oncostatin M/OSM Antibody (17001.31) - Low Endotoxin, Azide and BSA Free Summary

• Description: Novus Biologicals Mouse Oncostatin M/OSM Antibody (17001.31) - Low Endotoxin, Azide and BSA Free (NB120-10842) is a monoclonal antibody validated for use in IHC, WB and ELISA. Anti-Oncostatin M/OSM Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant full length protein (Human) expressed in E. coli.
• Localization: Secreted
• Specificity: Does not cross-react with recombinant human IL-6, IL-11, CNTF, LIF and recombinant mouse OSM.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: OSM
• Purity: Protein A purified
• Endotoxin Note: Endotoxin level is < 0.1 EU/ug antibody as determined by the LAL (Limulus amebocyte lysate) method.

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • ELISA 1:100-1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1 ug/ml
• Application Notes: The antibody neutralizes the biological activity of recombinant human OSM.
• Control:

  Oncostatin M/OSM Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 5% Trehalose
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for Oncostatin M/OSM Antibody (17001.31) - Low Endotoxin, Azide and BSA Free

• MGC20461
• oncostatin M
• oncostatin-M
• OSM

Background

Oncostatin M is an important growth regulating cytokine that affects variably a number of tumor and normal cells. Oncostatin M exerts inhibitory effects on the growth of A375 melanoma and other cancer cells, but augments the growth of normal fibroblasts, AIDS-related Kaposi sarcoma cells, and other certain cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Oncostatin M/OSM Antibody (NB120-10842)(1)

Publication using NB120-10842

• Varn FS, Johnson KC, Martinek J Et al. Glioma progression is shaped by genetic evolution and microenvironment interactions Cell 2022-06-01 [PMID: 35649412] (IHC-P, Human)
  
  Details:
  Citation using the Alexa Fluor 647 version of this antibody.

Bioinformatics

• Gene Symbol: OSM
• Entrez:
  • 5008(Human)
  • 18413(Mouse)