OMgp Antibody

Western Blot: OMgp Antibody [NB100-2557] - NB100-2557 (0.1ug/ml) staining of Human Amygdala lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

OMgp Antibody Summary

• Description: Novus Biologicals Goat OMgp Antibody (NB100-2557) is a polyclonal antibody validated for use in WB and ELISA. Anti-OMgp Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-KVTKIPKQYRTKE corresponding to internal region according to NP_002535.3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: OMG
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 0.1 - 0.3 ug/ml
• Application Notes: WB: Approx. 150 kDa band observed in human brain (amygdala) lysates (calculated MW of 49.6 kDa band according to NP_002535.3). The observed molecular weight corresponds to the glycosylated form.
• Control Peptide:

  OMgp Protein (NB100-2557PEP)

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for OMgp Antibody

• oligodendrocyte myelin glycoprotein
• OMG
• OMgp
• OMGPoligodendrocyte-myelin glycoprotein

Background

Myelin oligodendrocyte glycoprotein (MOG) is found on the surface of myelinating oligodendrocytes and external lamellae of myelin sheaths in the central nervous system. MOG is a minor component of the myelin sheath and is implicated in completion and maintenance of the myelin sheath and in cell-cell communication. MOG is found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes; peak expression has been observed between postnatal days 15 and 25, coincident with the period of active myelination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for OMgp Antibody (NB100-2557)(1)

Publication using NB100-2557

• McGee AW, Yang Y, Fischer QS et al. Experience-driven plasticity of visual cortex limited by myelin and Nogo receptor. Science 2005-09-30 [PMID: 16195464]

Bioinformatics

• Gene Symbol: OMG
• Entrez:
  • 4974(Human)
• Uniprot:
  • NP_002535.3(Human)