OCILRP2/CLEC2i Antibody [Alexa Fluor® 350]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 350

OCILRP2/CLEC2i Antibody [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant mouse OCILRP2/CLEC2i
  Thr77-Val217
  Accession # Q9WVF9
• Specificity: Detects mouse OCILRP2/CLEC2i in direct ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse OCIL is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for OCILRP2/CLEC2i Antibody [Alexa Fluor® 350]

• CLAX
• CLEC2i
• CLRG
• LLT1
• OCIL
• OCILRP2

Background

OCILRP2, also known as CLRG (C-type lectin related g) and CLEC2i (C-type lectin domain family 2, member i), is a type II transmembrane protein whose gene has been mapped to the natural killer gene complex (NKC) on mouse chromosome 6. By alternative splicing, multiple isoforms exist. OCIL RP2 is expressed on osteoclasts, chondrocytes and lymphoid cell types. It is a ligand for NKrp1f (KLRB1f), another NK receptor on the NKC. OCILRP2 inhibits osteoclast formation and can affect NK cell functions. The extracellular domain of mouse OCILRP2 shares 79% and 74% amino acid sequence identity with that of mouse OCILRP1 and OCIL, respectively. A human OCILRP2 ortholog has not been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.