OCILRP2/CLEC2i Products

Description

OCILRP2, also known as CLRG (C-type lectin related g) and CLEC2i (C-type lectin domain family 2, member i), is a type II transmembrane protein whose gene has been mapped to the natural killer gene complex (NKC) on mouse chromosome 6. By alternative splicing, multiple isoforms exist. OCIL RP2 is expressed on osteoclasts, chondrocytes and lymphoid cell types. It is a ligand for NKrp1f (KLRB1f), another NK receptor on the NKC. OCILRP2 inhibits osteoclast formation and can affect NK cell functions. The extracellular domain of mouse OCILRP2 shares 79% and 74% amino acid sequence identity with that of mouse OCILRP1 and OCIL, respectively. A human OCILRP2 ortholog has not been identified.

Bioinformatics

Uniprot	Q9WVF9
Product By Gene ID	29121
Alternate Names	CLAX CLEC2i CLRG LLT1 OCIL OCILRP2