OBFC2A Antibody [Janelia Fluor® 585]

Product Discontinued

OBFC2A Antibody [Janelia Fluor® 585] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1 to 50 of human oligonucleotide/oligosaccharide-binding fold containing 2A using the numbering given in entry NP_001026886.1 (GeneID 64859).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NABP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for OBFC2A Antibody [Janelia Fluor® 585]

• DKFZp667M1322
• FLJ13624
• FLJ22833
• hSSB2
• MGC111163
• oligonucleotide/oligosaccharide-binding fold containing 2A
• Oligonucleotide/oligosaccharide-binding fold-containing protein 2A
• Sensor of single-strand DNA complex subunit B2
• Sensor of ssDNA subunit B2
• SOSS complex subunit B2
• SOSS-B2
• SSB2Single-stranded DNA-binding protein 2

Background

OBFC2A is also known as hSSB2 or SSB2 and is a homolog of hSSB1 (OBFC2B). OBFC2A, as well as OBFC2B are single-stranded binding proteins that contain an oligonucleotide/oliosaccharide binding fold (OB-fold). OB-fold proteins associate with each other to form multi-OB-fold complexes that associate with DNA-processing complexes that participate in DNA damage repair and replication. OBFC2A has been shown to protect genomic stability, and it is hypothesized that its participation in the DNA damage response may involve RAD51 and the ATM signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NABP1