NUP62 Antibody (RL31) [Alexa Fluor® 750]

• Reactivity: Rt
• Applications: WB, ICC/IF
• Clone: RL31
• Clonality: Monoclonal
• Host: Armenian Hamster
• Conjugate: Alexa Fluor 750

NUP62 Antibody (RL31) [Alexa Fluor® 750] Summary

• Immunogen: O-linked glycoprotein-enriched fraction from rat liver nuclear envelopes raised in Armenian hamsters.
• Localization: Central region of the nuclear pore. During mitotic cell division, it associates with the poles of the mitotic spindle.
• Specificity: Detects the nucleoporin p62 O-linked glycoprotein in the p62 complex from rat tissues.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Armenian Hamster
• Gene: NUP62
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NUP62 Antibody (RL31) [Alexa Fluor® 750]

• DKFZp547L134,62 kDa nucleoporin
• FLJ20822
• FLJ43869
• IBSNp62
• MGC841
• nuclear pore glycoprotein p62
• nucleoporin 62kD
• nucleoporin 62kDa
• SNDINucleoporin Nup62

Background

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NUP62