Numb Antibody (4A7-A6)

Product Discontinued

Numb Antibody (4A7-A6) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: NUMB (AAH33824, 1 a.a. - 135 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
• Localization: Cell Membrane
• Specificity: NUMB - numb homolog (Drosophila)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: NUMB
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Numb Antibody (4A7-A6)

• h-Numb
• mnb
• m-numb
• numb (Drosophila) homolog
• numb homolog (Drosophila)
• Numb
• protein numb homolog
• Protein S171
• S171

Background

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NUMB
• Entrez:
  • 8650(Human)
• OMIM:
  • 603728(Human)
• Uniprot:
  • AAH33824(Human)