Nucleostemin Antibody

Product Discontinued

Nucleostemin Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 500 and the C-terminus (residue 549) of human Guanine Nucleotide Binding Protein-Like 3 (Nucleostemin) using the numbering given in entry NP_055181.3 (GeneID 26354).
• Marker: Embryonic Stem Cell Marker
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GNL3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100 - 1:500
• Application Notes: This antibody is useful for immunohistochemistry-paraffin Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections *The investigator should determine the optimal working dilution for a specific application.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Nucleostemin Antibody

• C77032
• E2IG3NNP47
• estradiol-induced nucleotide binding protein
• GNL3
• guanine nucleotide binding protein-like 3 (nucleolar)
• guanine nucleotide-binding protein-like 3
• MGC800
• Novel nucleolar protein 47
• NSE2-induced gene 3 protein
• Nucleolar GTP-binding protein 3
• Nucleostemin

Background

Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNL3
• Entrez:
  • 26354(Human)
  • 30877(Mouse)
• Uniprot:
  • NP_055181.3(Human)