Species: Hu, Mu, Bv
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Pm, Pm
Applications: ELISA, IHC
Host: Rabbit Polyclonal
Species: Rt
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AP
Description
Official Gene Symbol: NTSR2 Gen Bank Accession Number: NP_036476 Gene ID: 23620 (Human) Gene Map Locus: 2p25.1 (Human) NTR2 is a member of GPCR family. It contains a short N-terminal sequence, 7 transmembrane domains and a short cytoplasmic tail. It is a low affinity levocabastine-sensitive receptor for Neurotensin. Activation of NT2R by non-peptide agonists suggests that the receptor can couple to phospholipase C, phospholipase A2 and MAPK. Unlike NTR1, NTR2 is insensitive to GTP and has low sensitivity of sodium ions. Northern Blot analysis detected its expression in adult brain regions including the olfactory system, cerebral and crebellar cortices, hippocampus and hypothalamic nuclei. Its expression has also been found in low levels in kidney, uterus, heart and lung.
Bioinformatics
Product By Gene ID |
23620 |
Alternate Names |
- neurotensin receptor 2
- neurotensin receptor type 2
- neurotensin receptor, type 2
- NT-R-2
- NTR2Levocabastine-sensitive neurotensin receptor
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