Recombinant Mouse NT-3 Protein

Product Discontinued

Recombinant Mouse NT-3 Protein Summary

• Description: Recombinant bioactive protein containing 119 amino acids for Mouse Neurotrophin 3
  
  

  Source:E. coli
  Amino Acid Sequence:(P20181 )

• Preparation Method: Determined to be >97% pure by SDS-PAGE
• Details of Functionality: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: NTF3
• Purity: >97%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 13.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Sterile filtered and lyophilized
• Concentration: Lyoph
• Purity: >97%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in dH2O to a concentration of 0.1 - 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for long-term storage.

Alternate Names for Recombinant Mouse NT-3 Protein

• HDNF
• MGC129711
• Nerve growth factor 2
• Neurotrophic factor
• neurotrophin 3
• neurotrophin-3
• NGF2
• NGF-2
• NT3
• NT-3
• NTF3

Background

NT-3 is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. Murine NT-3 produced from E. coli contains 119 amino acid and having a molecular mass is 13.6 kDa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for NT-3 Recombinant Protein (NBP1-99227)(1)

Publication using NBP1-99227

• Vincent P, Young E, Edge A, Glowatzki E Auditory Hair Cells and Spiral Ganglion Neurons Regenerate Synapses with Refined Release Properties In Vitro bioRxiv 2023-10-09 [PMID: 38076928] (IHC-P)

Bioinformatics

• Gene Symbol: NTF3