NSP 5 alpha 3 alpha Antibody [DyLight 405]

Images

 
There are currently no images for NSP 5 alpha 3 alpha Antibody (NB100-517V).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

NSP 5 alpha 3 alpha Antibody [DyLight 405] Summary

Immunogen
An internal synthetic peptide made to the human NSP 5 alpha 3 alpha protein sequence (between residues 1-100). [UniProt# Q5M775]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SPECC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This NSP 5 alpha 3 alpha antibody is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot, where a band is seen at ~80 kDa. A second band may be seen at ~60 kDa. The specificity of this band is not known.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human. Immunogen has 83% homology with mouse and rat.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NSP 5 alpha 3 alpha Antibody [DyLight 405]

  • cytospin-B
  • CYTSBcytospin B
  • FLJ36955
  • HCMOGT-1
  • NSP
  • NSP5
  • Nuclear structure protein 5
  • sperm antigen HCMOGT 1
  • Sperm antigen HCMOGT-1
  • sperm antigen with calponin homology and coiled coil domains 1
  • sperm antigen with calponin homology and coiled-coil domains 1cytokinesis and spindle organization B
  • sperm antigen with calponin-like and coiled coil domains 1
  • structure protein NSP5a3a
  • structure protein NSP5a3b
  • structure protein NSP5b3a
  • structure protein NSP5b3b

Background

Nuclear structure protein 5 (NSP5) or NSP 5 alpha 3 alpha (NSP 5a3a) is a novel structural protein which has been found to be over-expressed differently in certain cancer cell lines such as: HT-29, MCF-7, Hela, HN30, Saos-2, CEM, and H23, however, it is barely detectable in normal body tissues except for testis wherein NSP 5a3a is highly expressed. NSP 5a3a interacts with cytoplasmic - nuclear proteins B23 which is known to implicate in multiple cellular processes such as mitosis, cell growth control, and apoptosis, ribosome biogenesis, and rRNA transcription/processing. NSP 5a3a also interacts with hnRNP-L which plays a role in RNA metabolism and rRNA processing. NSP proteins (NSP 5b3a, 5a3b, and 5b3b) have been implicated in several cellular activities such as intracellular trafficking, cellular/subcellular integrity, protein-protein interactions with other structural proteins as well as in protein complex stabilization and scaffolding thus facilitating homo or hetero dimerization of protein complexes. Over-expression of NSP 5a3a has been shown to induce apoptosis in head and neck carcinoma cell lines in particular in HN30 being p53 independent yet involving a novel p73 dependent mechanism wherein NSP 5a3a induces apoptosis through p73-DAXX and TRAF2-TRADD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-87003
Species: Hu, Rt
Applications: WB, IP, PLA
NBP1-59662
Species: Hu
Applications: WB, IHC, IHC-P
MAB4077
Species: Hu
Applications: WB, IHC
NBP1-82525
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-13306
Species: Hu
Applications: WB, IHC, IHC-P
MAB6967
Species: Hu
Applications: WB
NBP1-97677
Species: Hu, Mu, Rt, Po, Ha
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
NB110-61646
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
H00002316-M01
Species: Hu
Applications: WB, ELISA, IHC-P, PLA
NBP2-12553
Species: Hu
H00003845-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IP
AF1638
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC
MAB8630
Species: Hu
Applications: WB, IHC
NBP2-02450
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-32390
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NB600-41532
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP2-33498
Species: Hu
Applications: IHC, IHC-P
AF5430
Species: Mu
Applications: WB, IP
NBP2-00532
Species: Hu, Mu, Rt, Ca, Mk
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NB100-517V
Species: Hu
Applications: WB, ICC/IF

Publications for NSP 5 alpha 3 alpha Antibody (NB100-517V) (0)

There are no publications for NSP 5 alpha 3 alpha Antibody (NB100-517V).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for NSP 5 alpha 3 alpha Antibody (NB100-517V) (0)

There are no reviews for NSP 5 alpha 3 alpha Antibody (NB100-517V). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for NSP 5 alpha 3 alpha Antibody (NB100-517V) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional NSP 5 alpha 3 alpha Products

Bioinformatics Tool for NSP 5 alpha 3 alpha Antibody (NB100-517V)

Discover related pathways, diseases and genes to NSP 5 alpha 3 alpha Antibody (NB100-517V). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for NSP 5 alpha 3 alpha Antibody (NB100-517V)

Discover more about diseases related to NSP 5 alpha 3 alpha Antibody (NB100-517V).
 

Pathways for NSP 5 alpha 3 alpha Antibody (NB100-517V)

View related products by pathway.

Research Areas for NSP 5 alpha 3 alpha Antibody (NB100-517V)

Find related products by research area.

Blogs on NSP 5 alpha 3 alpha

There are no specific blogs for NSP 5 alpha 3 alpha, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our NSP 5 alpha 3 alpha Antibody [DyLight 405] and receive a gift card or discount.

Bioinformatics

Gene Symbol SPECC1