Nse2 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

Nse2 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 15 amino acids near the carboxy terminus of human MMS21.

  Source: Synthetic

  (Accession #: NP_775956)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: NSMCE2
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76263.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for Nse2 Antibody Blocking Peptide

• C8orf36
• E3 SUMO-protein ligase NSE2
• EC 6.3.2
• EC 6.3.2.-
• FLJ32440
• hMMS21
• methyl methanesulfonate sensitivity gene 21
• MMS21 homolog
• MMS21chromosome 8 open reading frame 36
• non-SMC element 2 homolog (MMS21, S. cerevisiae)
• Non-SMC element 2 homolog
• non-SMC element 2, MMS21 homolog (S. cerevisiae)
• Non-structural maintenance of chromosomes element 2 homolog
• NSE2

Background

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombination by recruiting theSMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteinssuch as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is requiredfor the prevention of DNA damage-induced apoptosis by facilitating DNA repair

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: NSMCE2