NRAMP1/SLC11A1 Antibody (910825) [PE/Cy7]

• Reactivity: Hu
• Applications: Flow
• Clone: 910825
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PE/Cy7

NRAMP1/SLC11A1 Antibody (910825) [PE/Cy7] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: NS0 mouse myeloma cell line transfected with human NRAMP1/SLC11A1
  Met1-Gly550
  Accession # NP_000569
• Specificity: Detects HEK293 human embryonic kidney cell line transfected with human NRAMP1/SLC11A1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC11A1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Cy is a registered trademark of Global Life Sciences Solutions Germany GmbH.

Alternate Names for NRAMP1/SLC11A1 Antibody (910825) [PE/Cy7]

• natural resistance-associated macrophage protein 1
• LSH
• member 1
• NRAMP 1
• NRAMP1
• NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1
• NRAMPnatural resistance-associated macrophage protein 1
• SLC11A1
• solute carrier family 11 (proton-coupled divalent metal ion transporters)

Background

"This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC11A1