NRAMP1/SLC11A1 Antibody (910825) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB, Flow, CyTOF-ready
• Clone: 910825
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

NRAMP1/SLC11A1 Antibody (910825) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: NS0 mouse myeloma cell line transfected with human NRAMP1/SLC11A1
  Met1-Gly550
  Accession # NP_000569
• Specificity: Detects HEK293 human embryonic kidney cell line transfected with human NRAMP1/SLC11A1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC11A1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for NRAMP1/SLC11A1 Antibody (910825) [CoraFluor™ 1]

• natural resistance-associated macrophage protein 1
• LSH
• member 1
• NRAMP 1
• NRAMP1
• NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1
• NRAMPnatural resistance-associated macrophage protein 1
• SLC11A1
• solute carrier family 11 (proton-coupled divalent metal ion transporters)

Background

"This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC11A1