Norrin/NDP Antibody [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: WB, IHC, B/N
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 646

Norrin/NDP Antibody [Janelia Fluor® 646] Summary

• Immunogen: E. coli-derived recombinant human Norrin
  Lys25-Ser133
  Accession # Q00604
• Specificity: Detects human Norrin in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Norrin is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: NDP
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Norrin/NDP Antibody [Janelia Fluor® 646]

• EVR2
• exudative vitreoretinopathy 2 (X-linked)
• FEVR
• ND
• NDP
• Norrie disease (pseudoglioma)
• Norrie disease protein
• Norrin
• X-linked exudative vitreoretinopathy 2 protein

Background

NDP (Norrie disease (pseudoglioma)) has a role in Wnt signaling pathway. Mutations in the NDP gene are related to health conditions such as Norrie disease and familial exudative vitreoretinopathy. NDP is known to have interactions with LRP5, TSPAN12, FZD4 and FZD8.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NDP