Nogo Receptor/NgR Antibody (202604) [Alexa Fluor® 700]

• Reactivity: Mu
• Applications: WB
• Clone: 202604
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 700

Nogo Receptor/NgR Antibody (202604) [Alexa Fluor® 700] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse NgR
  Cys27-Ser447
  Accession # Q99PI8
• Specificity: Detects mouse NgR in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human NgR.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Nogo Receptor/NgR Antibody (202604) [Alexa Fluor® 700]

• NgR
• NgR1
• Nogo R
• Nogo receptor
• Nogo-66 receptor
• NogoR
• NOGORUNQ330/PRO526
• reticulon 4 receptor
• reticulon-4 receptor
• RTN4R

Background

NgR,also named reticulon 4 receptor, is a glycosylphosphoinositol (GPI)-anchored proteinthat belongs to the family of leucine-rich repeat proteins. NgR plays an essential role inmediating axon growth inhibition induced by the myelin-derived proteins Nogo, myelinassociatedglycoprotein (MAG), and myelin oligodendrocyte glycoprotein (Omgp). Uponligand binding, NgR associates with and activates the p75 neurotrophin receptor(p75NTR), a tumor necrosis factor superfamily member (TNFRSF16).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.