Nodal Antibody

Product Discontinued

Nodal Antibody Summary

• Immunogen: Peptide with sequence ECPNPVGEEFH corresponding to internal region according to NP_060525.2.
• Localization: Secreted
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: NODAL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
  • Sandwich ELISA 1:100-1:2000
• Application Notes: EIA: Sandwich ELISA with increasing amount of recombinant NODAL captured by a rabbit antibody.
• Control:

  Nodal Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Nodal Antibody

• BMP-16
• MGC138230
• nodal homolog (mouse)
• nodal homolog
• Nodal
• nodal, mouse, homolog

Background

Nodal is encoded by this gene is a member of the TGF-beta superfamily. Studies of the mouse counterpart suggested that this gene may be essential for mesoderm formation and subsequent organization of axial structures in early embryonic development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Nodal Antibody (NB100-74578)(1)

Publication using NB100-74578

• Hendrix MJ, Seftor EA, Seftor RE et al. Reprogramming metastatic tumour cells with embryonic microenvironments. Nat Rev Cancer 2007-04-01 [PMID: 17384580]

Bioinformatics

• Gene Symbol: NODAL
• Entrez:
  • 4838(Human)
  • 18119(Mouse)
  • 294503(Rat)
• Uniprot:
  • Q96S42()