NMDAR2D Antibody

• Reactivity: Hu, Mu, Rt
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

NMDAR2D Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence C-TRRGSAHFSSLESE corresponding to C-Terminus according to NP_000827.2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: GRIN2D
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments gave an approx. 80 kDa band in human brain (cerebellum) and in mouse brain and rat brain lysates after 0.02 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 144 kDa band according to NP_000827.2. The 80 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for NMDAR2D Antibody

• EB11
• EB11estrogen receptor binding CpG island
• GluN2D
• glutamate receptor, ionotropic, N-methyl D-aspartate 2D
• GRIN2D
• NMDA epsilon 4
• NMDAR2D
• NMDAR2DN-methyl-d-aspartate receptor subunit 2D
• N-methyl D-aspartate receptor subtype 2D
• NR2D
• NR2Dglutamate [NMDA] receptor subunit epsilon-4

Background

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NMDAR2D Antibody (NBP1-00197)(1)

Publication using NBP1-00197

• Clarke RJ, Johnson JW. NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock. J Neurosci 2006-05-24 [PMID: 16723541]

Bioinformatics

• Gene Symbol: GRIN2D
• Entrez:
  • 2906(Human)
  • 14814(Mouse)
  • 24412(Rat)
• Uniprot:
  • NP_000827.2(Human)