NMDAR2A Antibody (T7) - Azide and BSA Free

• Reactivity: Hu, Rt
• Applications: WB, ICC/IF, IHC
• Clone: T7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1.0 mg/ml

NMDAR2A Antibody (T7) - Azide and BSA Free Summary

• Description: Relevant Entrez Gene Numbers: NM_000833.2
• Immunogen: Amino acid region 1099-1213 from human NMDAR2A produced as a GST fusion protein.
• Specificity: Amino acid region 1099-1213 from human NMDAR2A produced as a GST fusion protein.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRIN2A
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 2.5-5 ug/ml
  • Immunohistochemistry 2.5-5 ug/ml
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1-5 ug/ml
• Application Notes: Immunohistochemistry (light and EM) on 4% paraformaldehyde & 0.125% glutaraldehyde fixed tissue.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Notes

Relevant Entrez Gene Numbers: NM_000833.2

Alternate Names for NMDAR2A Antibody (T7) - Azide and BSA Free

• GluN2A
• glutamate receptor, ionotropic, N-methyl D-aspartate 2A
• hNR2A
• NMDA receptor subtype 2A
• N-methyl D-aspartate receptor subtype 2A
• N-methyl-D-aspartate receptor subunit 2A
• subunit epsilon-1

Background

The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIN2A
• Uniprot:
  • Q12879(Human)