NMDA R, NR1 Subunit Antibody (1031915) [Alexa Fluor™ Plus 647]

• Clone: 1031915
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 647

NMDA R, NR1 Subunit Antibody (1031915) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects mouse GRIN1/NMDAR1 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NMDA R, NR1 Subunit Antibody (1031915) [Alexa Fluor™ Plus 647]

• GluN1
• GRIN1
• MRD8
• NDHMSD
• NDHMSR;NMD-R1
• NMDA R, NR1 Subunit
• NMDA1
• NMDAR1
• NMD-R1
• NR1

Background

Grin-1 is a critical component of NMDA receptors.  Expressed in the brain, these components play a key role in plasticity of synapses, which is believed to underlie memory and learning.  Missense variants of the receptor components cause similar syndromes with varying severity of intellectual impairment, autism, epilepsy, and motor dysfunction.  In Mice with reduced NMDA receptor activity, schizophrenia-like behaviors are revealed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.