NLRP11 Antibody Blocking Peptide

Product Discontinued

NLRP11 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 15 amino acids near the carboxy terminus of human NALP11.

  Source: Synthetic

  (Accession #: NP_659444)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: NLRP11
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76292.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for NLRP11 Antibody Blocking Peptide

• CLR19.6
• NACHT, leucine rich repeat and PYD containing 11
• NALP11NACHT, LRR and PYD domains-containing protein 11
• NLR family, pyrin domain containing 11
• NOD17PYPAF7
• Nucleotide-binding oligomerization domain protein 17
• nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 11
• PAAD- and NACHT-containing protein 10
• PAAD- and NACHT-containing protein 10B
• PAAD-and NACHT domain-containing protein 10
• PAN10FLJ26273
• PYPAF6NACHT, LRR and PYD containing protein 11
• PYRIN-containing APAF1-like protein 6

Background

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: NLRP11