NLRP11 Antibody

Product Discontinued

NLRP11 Antibody Summary

• Immunogen: Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human NALP11. The immunogen is located within the last 50 amino acids of NALP11.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NLRP11
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 20 ug/ml
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for NLRP11 Antibody

• CLR19.6
• NACHT, leucine rich repeat and PYD containing 11
• NALP11NACHT, LRR and PYD domains-containing protein 11
• NLR family, pyrin domain containing 11
• NOD17PYPAF7
• Nucleotide-binding oligomerization domain protein 17
• nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 11
• PAAD- and NACHT-containing protein 10
• PAAD- and NACHT-containing protein 10B
• PAAD-and NACHT domain-containing protein 10
• PAN10FLJ26273
• PYPAF6NACHT, LRR and PYD containing protein 11
• PYRIN-containing APAF1-like protein 6

Background

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP11 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP11, it has been suggested that it has been associated with Crohn's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NLRP11
• Uniprot:
  • NP_659444(Human)