NKX2.5 Antibody Pair

Product Discontinued

NKX2.5 Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00001482-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NKX2-5.
  
  
• Capture antibody: rabbit MaxPab affinity purified polyclonal anti-NKX2-5 (100 ug)
• Detection antibody: mouse monoclonal anti-NKX2-5 IgG1 Kappa (20 ug)
• Marker: Stem Cell Marker
• Standard Curve Range: 3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: NKX2-5

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NKX2.5 Antibody Pair

• cardiac-specific homeo box
• cardiac-specific homeobox 1
• Cardiac-specific homeobox
• CHNG5
• CSX1
• CSXFLJ97195
• FLJ52202
• FLJ99536
• Homeobox protein CSX
• Homeobox protein NK-2 homolog E
• homeobox protein Nkx-2.5
• NK2 transcription factor related, locus 5 (Drosophila)
• NKX2.5
• NKX2.5FLJ97166
• NKX2-5
• NKX2E
• NKX2EFLJ97197
• NKX4-1
• tinman paralog

Background

Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: NKX2-5