NKG2A/CD159a/KLRC1 Antibody Summary
Synthetic peptide corresponding to a region within amino acids 171 and 233 of KLRC1 (Uniprot ID#P26715)
Membrane; Single-pass type II membrane protein
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7).
Immunogen affinity purified
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Human. Rhesus Monkey (100%), Chimpanzee (100%).
Alternate Names for NKG2A/CD159a/KLRC1 Antibody
- CD159 antigen-like family member A
- CD159a antigen
- C-lectin type II protein
- killer cell lectin-like receptor subfamily C, member 1
- natural killer cell lectin
- natural killer group protein 2
- NK cell receptor A
- NKG2-1/B activating NK receptor
- NKG2-A/B type II integral membrane protein
- NKG2-A/B-activating NK receptor
- NKG2-A/NKG2-B type II integral membrane protein
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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