NGFRAP1/BEX3/NADE Antibody

Images

 
Western Blot: NGFRAP1/BEX3/NADE Antibody [NBP1-31652] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: H1299 15% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: NGFRAP1/BEX3/NADE Antibody [NBP1-31652] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: NGFRAP1/BEX3/NADE Antibody [NBP1-31652] - Paraffin-embedded H1299 Xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

NGFRAP1/BEX3/NADE Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human NADE. The exact sequence is proprietary.
Localization
Nucleus, Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BEX3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Control
NGFRAP1/BEX3/NADE Knockout 293T Cell Lysate

Reactivity Notes

Expected cross reactivity based on sequence homology: Rhesus Monkey (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for NGFRAP1/BEX3/NADE Antibody

  • BEX3
  • BEX3p75NTR-associated cell death executor
  • Brain-expressed X-linked protein 3
  • DXS6984EX-linked 3
  • HGR74
  • NADE
  • nerve growth factor receptor (TNFRSF16) associated protein 1
  • Nerve growth factor receptor-associated protein 1
  • NGFRAP1
  • Ovarian granulosa cell 13.0 kDa protein HGR74
  • ovarian granulosa cell protein (13kD)
  • protein BEX3

Background

May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.; SUBUNIT: Self-associates. Interacts with 14-3-3 epsilon. Interacts with DIABLO/SMAC. Binds to the DEATH domain of p75NTR/NGFR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Video Protocols

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ICC/IF Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol BEX3
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