NGFRAP1/BEX3/NADE Products

Antibodies
NGFRAP1/BEX3/NADE Antibody (6 ...
NGFRAP1/BEX3/NADE Antibody (672911)
MAB6858
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
NGFRAP1/BEX3/NADE Antibody
NGFRAP1/BEX3/NADE Antibody
NBP1-31652
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NGFRAP1/BEX3/NADE Antibody
NGFRAP1/BEX3/NADE Antibody
NBP1-77149
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
NGFRAP1/BEX3/NADE Overexpress ...
NGFRAP1/BEX3/NADE Overexpression L...
H00027018-T01
Species: Hu
Applications: WB
NGFRAP1/BEX3/NADE Overexpress ...
NGFRAP1/BEX3/NADE Overexpression L...
NBP2-04519
Applications: WB
NGFRAP1/BEX3/NADE Overexpress ...
NGFRAP1/BEX3/NADE Overexpression L...
NBP2-10324
Applications: WB
Proteins
Recombinant Human NGFRAP1/BEX ...
Recombinant Human NGFRAP1/BEX3/NAD...
H00027018-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human NGFRAP1/BEX ...
Recombinant Human NGFRAP1/BEX3/NAD...
H00027018-Q01
Species: Hu
Applications: WB, ELISA, PA
NGFRAP1/BEX3/NADE Recombinant ...
NGFRAP1/BEX3/NADE Recombinant Prot...
NBP1-89987PEP
Species: Hu
Applications: AC
RNAi
NGFRAP1/BEX3/NADE RNAi
NGFRAP1/BEX3/NADE RNAi
H00027018-R04
Species: Hu
Applications: RNAi, RNAi SP
NGFRAP1/BEX3/NADE RNAi
NGFRAP1/BEX3/NADE RNAi
H00027018-R05
Species: Hu
Applications: RNAi, RNAi SP
NGFRAP1/BEX3/NADE RNAi
NGFRAP1/BEX3/NADE RNAi
H00027018-R06
Species: Hu
Applications: RNAi, RNAi SP

Description

The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF). The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR. Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac). Coexpression of NADE and Smac promotes TRAIL-induced apoptosis and inhibits XIAP-mediated Smac ubiquitization. It has been suggested that it is this interaction between NADE and Smac that allows apoptosis to proceed. Finally, although initially discovered as an mRNA expressed in ovarian granulosa cells, NADE has been suggested to play a role in the neuronal death seen in epileptic brain damage.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 27018
Alternate Names
  • Nerve growth factor receptor-associated protein 1
  • protein BEX3
  • Brain-expressed X-linked protein 3
  • ovarian granulosa cell protein (13kD)
  • HGR74
  • DXS6984EX-linked 3
  • BEX3p75NTR-associated cell death executor
  • Ovarian granulosa cell 13.0 kDa protein HGR74
  • nerve growth factor receptor (TNFRSF16) associated protein 1

Research Areas for NGFRAP1/BEX3/NADE

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for NGFRAP1/BEX3/NADE

Learn more about PTMs related to NGFRAP1/BEX3/NADE.

Phosphorylation
Cleavage
Methylation
Ubiquitination

Bioinformatics Tool for NGFRAP1/BEX3/NADE

Discover related pathways, diseases and genes to NGFRAP1/BEX3/NADE. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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