NFKBIL1 Antibody

Images

 
Western Blot: NFKBIL1 Antibody [NBP1-70344] - analysis of NFKBIL1. Lanes 1 and 2 show HeLa cell lysate probed with pre-immune sera (1:5000) and NFKBIL1 polyclonal antibody (3 ug/ml), respectively.

Product Details

Summary
Reactivity Hu, Am, Bv, Ca, Eq, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

NFKBIL1 Antibody Summary

Immunogen
Amino acids RRYLRVQQVRWHPDRFLQR (331-349) of human NFKBIL1 were used as the immunogen.
Specificity
The amino acid sequence used as immunogen is 100% homologous in human, new world monkey, panda, mouse lemur, chimpanzee, cow, dog, orangutan, rhesus monkey, wild pig, 95% homologous in horse, rat, mouse, 89% homologous in frog, opossum, sea anemone and 74% homologous in platypus and carolina anole.There are multiple isoforms of this protoein. The amino acid sequenced used as immunogen is provided to help researchers determine suitability of this antibody for their testing.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NFKBIL1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2-4 ug/ml

Reactivity Notes

Reacts with Carolina anole, Chimpanzee, Cow, Dog, Frog, Horse and Human. Predicted to react with Sea Urchin, Fresh water polyp and Acorn worm.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for NFKBIL1 Antibody

  • IkappaBL
  • I-kappa-B-like protein
  • IKBLikappaBL
  • Inhibitor of kappa B-like protein
  • LST1
  • NF-kappa-B inhibitor-like protein 1
  • nuclear factor of kappa light polypeptide gene enhancer in B-cellsinhibitor-like 1NFKBIL

Background

NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers and co-localized in CD68+ and CD3+, but not Factor VIII+ cells. It is reported that defects in NFKBIL1 expression causes of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and affects the joints. Rheumatoid arthritis (RA) is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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NFKBIL1 NBP1-70344

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Bioinformatics

Gene Symbol NFKBIL1
Uniprot