NFKBIL1 Antibody Summary
Amino acids RRYLRVQQVRWHPDRFLQR (331-349) of human NFKBIL1 were used as the immunogen.
The amino acid sequence used as immunogen is 100% homologous in human, new world monkey, panda, mouse lemur, chimpanzee, cow, dog, orangutan, rhesus monkey, wild pig, 95% homologous in horse, rat, mouse, 89% homologous in frog, opossum, sea anemone and 74% homologous in platypus and carolina anole.There are multiple isoforms of this protoein. The amino acid sequenced used as immunogen is provided to help researchers determine suitability of this antibody for their testing.
Protein A purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Reacts with Carolina anole, Chimpanzee, Cow, Dog, Frog, Horse and Human. Predicted to react with Sea Urchin, Fresh water polyp and Acorn worm.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.05% BSA
0.05% Sodium Azide
Protein A purified
Alternate Names for NFKBIL1 Antibody
- I-kappa-B-like protein
- Inhibitor of kappa B-like protein
- NF-kappa-B inhibitor-like protein 1
- nuclear factor of kappa light polypeptide gene enhancer in B-cellsinhibitor-like 1NFKBIL
NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers and co-localized in CD68+ and CD3+, but not Factor VIII+ cells. It is reported that defects in NFKBIL1 expression causes of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and affects the joints. Rheumatoid arthritis (RA) is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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