NFATC1/NFAT2 [p Ser172] Antibody (679340)

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Western Blot: NFATC1/NFAT2 [p Ser172] Antibody (679340) [MAB5640] - Lysates of Jurkat human acute T cell leukemia cell line untreated (-) or treated (+) with 200 nm PMA and 1 um Ionomycin for 24 hours. PVDF Membrane was ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
679340
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

NFATC1/NFAT2 [p Ser172] Antibody (679340) Summary

Immunogen
Phosphopeptide containing the human S172 site.
Modification
p Ser172
Specificity
Detects human NFATC1 in direct ELISAs.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NFATC1
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Reviewed Applications
Read 1 Review rated 4
using
MAB5640 in the following application:

Publications
Read Publication using
MAB5640 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NFATC1/NFAT2 [p Ser172] Antibody (679340)

  • MGC138448
  • NFAT transcription complex cytosolic component
  • NFAT2
  • NFAT2cytoplasmic 1
  • NFATC
  • NF-ATC
  • NFATC1
  • NF-ATc1
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Background

NFATC1 (Nuclear factor of activated T cells c1), also called NFAT2a, is a 120 kDa, 943 amino acid member of the NFAT family of transcription factors. NFATC1 is found in T cells and mast cells, and regulates cytokine transcription. NFATC1 is normally cytoplasmic and phosphorylated at Ser172 within a transactivation domain. Upon a rise in intracellular Ca++, dephosphorylation occurs via calcineurin, and NFATC1 enters the nucleus. Multiple isoforms exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NFATC1/NFAT2 Antibody (MAB5640)(1)

Review for NFATC1/NFAT2 Antibody (MAB5640) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using MAB5640:
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(1)
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Images Ratings Applications Species Date Details
Western Blot NFATC1/NFAT2 MAB5640
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4
reviewed by:
Anonymous
WB Mouse 07/19/2017
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Summary

ApplicationWestern Blot
Sample TestedSkeletal muscle
SpeciesMouse

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Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

Anonymous
07/19/2017
Application: WB
Species: Mouse

Bioinformatics

Gene Symbol NFATC1