NFATC1/NFAT2 Antibody (679340) [Alexa Fluor® 405]

• Reactivity: Hu
• Clone: 679340
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

NFATC1/NFAT2 Antibody (679340) [Alexa Fluor® 405] Summary

• Specificity: Detects human NFATC1 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NFATC1/NFAT2 Antibody (679340) [Alexa Fluor® 405]

• MGC138448
• NFAT transcription complex cytosolic component
• NFAT2
• NFAT2cytoplasmic 1
• NFATC
• NF-ATC
• NFATC1
• NF-ATc1
• nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Background

NFATC1 (Nuclear factor of activated T cells c1), also called NFAT2a, is a 120 kDa, 943 amino acid member of the NFAT family of transcription factors. NFATC1 is found in T cells and mast cells, and regulates cytokine transcription. NFATC1 is normally cytoplasmic and phosphorylated at Ser172 within a transactivation domain. Upon a rise in intracellular Ca⁺⁺, dephosphorylation occurs via calcineurin, and NFATC1 enters the nucleus. Multiple isoforms exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.