Neprilysin/CD10 Antibody (56C6)

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Immunohistochemistry-Paraffin: CD10 Antibody (56C6) [NB600-1061] - Staining of Human renal cell carcinoma

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clone
56C6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Neprilysin/CD10 Antibody (56C6) Summary

Immunogen
Prokaryotic recombinant fusion protein corresponding to the external of the CD10 glycoprotein
Localization
Cell membrane
Specificity
This antibody is specific to human CD10 antigen of 100 kDa, also known as common acute lymphocytic leukemia antigen (CALLA). CD10 antigen has been identified on the surface of early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MME
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:20-1:30
Application Notes
For IHC: Use high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 is required prior to immunostaining of formalin fixed paraffin embedded tissue sections.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tissue culture supernatant
Preservative
Sodium Azide
Purity
Tissue culture supernatant

Alternate Names for Neprilysin/CD10 Antibody (56C6)

  • Atriopeptidase
  • CALLA
  • CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)
  • CD10 antigen
  • CD10
  • CD10)
  • CD10membrane metallo-endopeptidase variant 1
  • Common acute lymphocytic leukemia antigen
  • DKFZp686O16152
  • EC 3.4.24
  • EC 3.4.24.11
  • Enkephalinase
  • EPN
  • Leu-19
  • membrane metallo-endopeptidase variant 2
  • membrane metallo-endopeptidase
  • MGC126681
  • MGC126707
  • MME
  • NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA
  • Neprilysin
  • Neutral Endopeptidase 24.11
  • Neutral endopeptidase
  • NKH1
  • SFE
  • Skin fibroblast elastase

Background

Human CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt's lymphoma and chronic myelocytic leukemia. CD10 also marks normal early lymphoid progenitor cells, immature B-cells in adult bone marrow and germinal cells in normal tonsil and normal lymphoid tissue. It is also expressed in some non-lymphoid tissues such as fibroblasts, breast myoepithelium and brush border of kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MME
Entrez
Uniprot