NCOR1 Antibody (NBP1-67715)

Images

 
Western Blot: NCOR Antibody [NBP1-67715] - Analysis of extracts from MDA-MB-435 cells, using NCOR Antibody. The lane on the right is treated with the synthesized peptide.
Immunohistochemistry-Paraffin: NCOR Antibody [NBP1-67715] - Analysis of paraffin-embedded human breast carcinoma tissue, using NCOR Antibody. The picture on the right is treated with the synthesized peptide.

Product Details

Summary
Product Discontinued
View other related NCOR1 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-67715
    • Availability
      Product Discontinued

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NCOR1 Antibody Summary

Immunogen
The antiserum was produced against synthesized peptide derived from human NCoR1. The immunogen region is: N-terminal.
Specificity
NCoR1 Antibody detects endogenous levels of total NCoR1 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
NCOR1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • ELISA 1:20000
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
270 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human,Mouse

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NCOR1 Antibody

  • hN-CoR
  • KIAA1047
  • KIAA1047N-CoR1
  • MGC104216
  • N-CoR
  • NCOR1
  • N-CoRhCIT529I10
  • nuclear receptor corepressor 1
  • nuclear receptor co-repressor 1
  • thyroid hormone- and retinoic acid receptor-associated corepressor 1
  • TRAC1

Background

Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Research Areas for NCOR1 Antibody (NBP1-67715)

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Blogs on NCOR1.

Muscular Dystrophy Regulation: Ezh2, NCoR-1
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur...  Read full blog post.

NCOR & EZH2 in Muscular Dystrophy
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur...  Read full blog post.

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Bioinformatics

Gene Symbol NCOR1
Entrez
OMIM
Uniprot