NCOR1 Products

Description

NCOR encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Bioinformatics

Entrez	9611 Human 20185 Mouse
Uniprot	O75376 Human
Product By Gene ID	9611
Alternate Names	hN-CoR KIAA1047 KIAA1047N-CoR1 MGC104216 N-CoR NCOR1 N-CoRhCIT529I10 nuclear receptor corepressor 1 nuclear receptor co-repressor 1 thyroid hormone- and retinoic acid receptor-associated corepressor 1 TRAC1

Research Areas for NCOR1

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Transcription Factors and Regulators

Related NCOR1 Blog Posts

Check out the latest blog posts on NCOR1.

Muscular Dystrophy Regulation: Ezh2, NCoR-1 Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur...    Read more.

NCOR & EZH2 in Muscular Dystrophy Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur...    Read more.

Read more NCOR1 related blogs.