NAIP Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

NAIP Antibody Summary

Immunogen
Peptide with sequence QKASDERISQFDHN-C corresponding to N-Terminus according to NP_004527.2.
Epitope
QKASDERISQFDHN-C
Specificity
This antibody is expected to recognize reported isoform 1 (NP_004527.2).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
NAIP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:1000
Application Notes
WB: Preliminary experiments in lysates of A549 and HeLa and in lysates of human breast cancer gave no specific signal but low background.
Publications
Read Publication using NBP1-52155.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for NAIP Antibody

  • baculoviral IAP repeat-containing 1
  • BIRC1
  • BIRC1baculoviral IAP repeat-containing protein 1
  • FLJ18088
  • FLJ42520
  • FLJ58811
  • NAIP
  • Neuronal apoptosis inhibitory protein
  • NLR family, apoptosis inhibitory protein
  • NLR family, BIR domain containing 1
  • NLRB1
  • nucleotide-binding oligomerization domain, leucine rich repeat and BIR domaincontaining 1
  • psi neuronal apoptosis inhibitory protein
  • psiNAIP

Background

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NAIP Antibody (NBP1-52155)(1)


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Secondary Antibodies

 

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Blogs on NAIP.

Survivin - an inhibitor of apoptosis protein
Survivin is an anti-apoptotic protein which is the smallest protein within a large family of proteins including X-linked IAP, c-IAP1 and 2, IAP-like protein-2, melanoma IAP, NAIP, and Livin. Survivin is responsible for a wide range of basic cellula...  Read full blog post.

Survivin is thrivin'
The survivin anti-apoptotic protein is the smallest member of a large family of proteins such as X-linked IAP, c-IAP1 and 2, IAP-like protein-2, melanoma IAP, Livin, and NAIP. Survivin regulates basic physiological events such as the cell cycle, tumor...  Read full blog post.

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Bioinformatics

Gene Symbol NAIP
Entrez
Uniprot