Myosin heavy chain 11 Antibody (MYH11/923 + SMMS-1) - Azide and BSA Free

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications Flow, IHC-P, CyTOF-ready, ICC/IF
Clone
MYH11/923 + SMMS-1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1.0 mg/ml

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Myosin heavy chain 11 Antibody (MYH11/923 + SMMS-1) - Azide and BSA Free Summary

Immunogen
Recombinant human MYH11 protein (MYH11/923); Human uterus extract (SMMS-1)
Localization
Cytoplasmic
Marker
Leiomyosarcoma & Myoepithelial Cell Marker
Specificity
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
MYH11
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml
  • Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
  • CyTOF-ready
  • Immunofluorescence 0.5 - 1.0 ug/ml
Application Notes
Hu-chromosome location: 16p13.11 Molecular weight of antigen: 205kDa (MHC-1) and 200kDa (MHC-2) Immunohistochemistry-Paraffin 0.5 - 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10 - 20 min followed by cooling at RT for 20 minutes.

Reactivity Notes

Human, Rat. Predicted to have broad species reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for Myosin heavy chain 11 Antibody (MYH11/923 + SMMS-1) - Azide and BSA Free

  • AAT4
  • FAA4
  • MYH11 myosin, heavy chain 11, smooth muscle
  • MYH11
  • SMHC
  • SMMHC
  • Smooth muscle myosin heavy chain

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MYH11