Myosin heavy chain 11 Products

Antibodies
Myosin heavy chain 11 Antibod ...
Myosin heavy chain 11 Antibody
21370002
Species: Hu
Applications: WB, ELISA, ChIP
Host: Rabbit Polyclonal
Myosin heavy chain 11 Antibod ...
Myosin heavy chain 11 Antibody
NBP1-87025
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal

Description

The protein encoded by the MYH11 gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. MYH11 functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Bioinformatics

Uniprot Human
Product By Gene ID 4629
Alternate Names
  • Smooth muscle myosin heavy chain
  • SMMHC
  • SMHC
  • FAA4
  • AAT4
  • MYH11
  • MYH11 myosin, heavy chain 11, smooth muscle

Research Areas for Myosin heavy chain 11

Find related products by research area and learn more about each of the different research areas below.

Hypoxia
Stem Cell Markers

PTMs for Myosin heavy chain 11

Learn more about PTMs related to Myosin heavy chain 11.

Acetylation
Methylation

Bioinformatics Tool for Myosin heavy chain 11

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