MYOM1 Antibody - BSA Free

Western Blot: MYOM1 Antibody - BSA Free [NBP3-46962] - Mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with (MYOM1 antibody) at dilution of 1:600

Immunohistochemistry: MYOM1 Antibody - BSA Free [NBP3-46962] - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using (MYOM1 Antibody) at dilution of 1:50

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

MYOM1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit MYOM1 Antibody - BSA Free (NBP3-46962) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: myomesin 1, 185 kDaa. (Uniprot# P52179)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MYOM1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 190 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for MYOM1 Antibody - BSA Free

• 190 kDa connectin-associated protein
• 190 kDa titin-associated protein
• EH-myomesin
• MGC134946
• MGC134947
• myomesin (M-protein) 1 (190kD)
• myomesin 1 (skelemin) (185kD)
• myomesin 1 (skelemin) 185kDa
• myomesin 1, 185kDa
• Myomesin family member 1
• myomesin-1
• SKELEMIN

Background

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYOM1